Mast Cells and Immunological Skin Diseases

Mast cells and immunological skin diseases.

Mast cells play an important role in both adaptive and innate immunity, and a large body of literature demonstrates their functions in skin immunity. This article reviews the literature on the role of this cell type in the pathogenesis of a number of immunological skin diseases, including contact dermatitis, atopic dermatitis, immunobullous disease, scleroderma, and chronic graft-vs.-host disea...

Immunological skin diseases: Boundaries and relationships

About half of skin diseases are immune-related. Immunological skin diseases are crudely divided into infectious, allergic, autoimmune and other types based on the etiology, pathogenesis and immune responses. While their distinction is not absolute, cause-effect and inter-relationship exist among them. This review focuses on the intrinsic associations among different categories of skin immune di...

[Mast cells in allergic diseases].

Skin Mast Cell Promotion in Random Skin Flaps in Rats using Bone Marrow Mesenchymal Stem Cells and Amniotic Membrane

Background: Skin flap procedures are employed in plastic surgery, but failure can lead to necrosis of the flap. Studies have used bone marrow mesenchymal stem cells (BM-MSCs) to improve flap viability. BM-MSCs and acellular amniotic membrane (AAM) have been introduced as alternatives. The objective of this study was to evaluate the effect of BM-MSCs and AAM on mast cells of random skin flaps (R...

Biological and Immunological Reactions in Parasitic Diseases

Processed antigen reacts selectively with lymphocytes bearing .appropriate surface immunoglobulin molecules resulting in the clonal proliferation of these cells, produc­ing circulating immunoglobulin (humoral immunity) or non-circulating immunoglobulins (cellular immunity).  High levels of circulating immunoglobulins (lgM & lgG) occur in protozoa and helminths infections. Reaginic antibodies a...